TOWARDS ONE STANDARD TREATMENT FOR UNCOMPLICATED PLASMODIUM FALCIPARUM AND PLASMODIUM VIVAX MALARIA: PERSPECTIVES FROM AND FOR THE PERUVIAN AMAZON

Towards one standard treatment for uncomplicated Plasmodium falciparum and Plasmodium vivax malaria: Perspectives from and for the Peruvian Amazon

Malaria continues to wreak havoc in the Peruvian Amazon.Lengthy research efforts have brought important lessons on its particular epidemiology: the heterogeneous levels of transmission, the large reservoir of both asymptomatic and submicroscopic infections, the co-transmission of Plasmodium vivax and Plasmodium falciparum in the same areas, and the

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Pro-con of proton: Dosimetric advantages of intensity-modulation over passive scatter for thoracic malignancies

The use of passively scattered proton therapy (PSPT) or intensity modulated proton therapy (IMPT) opens the potential for dose fbd191blrc escalation or critical structure sparing in thoracic malignancies.While the latter offers greater dose conformality, dose distributions are subjected to greater uncertainties, especially due to interplay effects.

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Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O6-Alkylguanine-DNA Alkyltransferase Activity

Human O6-alkylguanine-DNA alkyltransferase (hAGT) is a DNA repair protein that reverses the effects of alkylating agents by removing DNA adducts from fox 985-24-100 reservoir shock the O6 position of guanine.Here, we developed a real-time fluorescence hAGT activity assay that is based on the detection of conformational changes of the thrombin-bindi

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